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文书解析 | 看“Pickle Truck”如何驶入名校

2020-06-09 10:33:38 来源:江博教育 作者:江博教育

生活中,甜酸苦辣咸,轮番上阵。当你经历不同的人生体验,是否想到这些五味杂陈的生活阅历也可以成为不错的文书素材呢?让我们来看看今天的主人公,从儿时故事书中读到的“Pickle truck”,到他不停的去找寻他人生和学术领域上的goldbug,再到最终他梦想的“酸黄瓜”货车,是如何最终驶入了Tufts的大门吧!相信你也会从中受到启发,开始思考自己人生中的goldbug吧!




Renner Kwittken '23


Armonk, NY


My first dream job was to be a pickle truck driver. I saw it in my favorite book, Richard Scarry's "Cars and Trucks and Things That Go," and for some reason, I was absolutely obsessed with the idea of driving a giant pickle. Much to the discontent of my younger sister, I insisted that my parents read us that book as many nights as possible so we could find goldbug, a small little golden bug, on every page. I would imagine the wonderful life I would have: being a pig driving a giant pickle truck across the country, chasing and finding goldbug. I then moved on to wanting to be a Lego Master. Then an architect. Then a surgeon.


Then I discovered a real goldbug: gold nanoparticles that can reprogram macrophages to assist in killing tumors, produce clear images of them without sacrificing the subject, and heat them to obliteration.


Suddenly the destination of my pickle was clear.


I quickly became enveloped by the world of nanomedicine; I scoured articles about liposomes, polymeric micelles, dendrimers, targeting ligands, and self-assembling nanoparticles, all conquering cancer in some exotic way. Completely absorbed, I set out to find a mentor to dive even deeper into these topics. After several rejections, I was immensely grateful to receive an invitation to work alongside Dr. Sangeeta Ray at Johns Hopkins.



In the lab, Dr. Ray encouraged a great amount of autonomy to design and implement my own procedures. I chose to attack a problem that affects the entire field of nanomedicine: nanoparticles consistently fail to translate from animal studies into clinical trials. Jumping off recent literature, I set out to see if a pre-dose of a common chemotherapeutic could enhance nanoparticle delivery in aggressive prostate cancer, creating three novel constructs based on three different linear polymers, each using fluorescent dye (although no gold, sorry goldbug!). Though using radioactive isotopes like Gallium and Yttrium would have been incredible, as a 17-year-old, I unfortunately wasn't allowed in the same room as these radioactive materials (even though I took a Geiger counter to a pair of shoes and found them to be slightly dangerous).


 

I hadn't expected my hypothesis to work, as the research project would have ideally been led across two full years. Yet while there are still many optimizations and revisions to be done, I was thrilled to find -- with completely new nanoparticles that may one day mean future trials will use particles with the initials "RK-1" – that cyclophosphamide did indeed increase nanoparticle delivery to the tumor in a statistically significant way.


A secondary, unexpected research project was living alone in Baltimore, a new city to me, surrounded by people much older than I. Even with moving frequently between hotels, AirBnB's, and students' apartments, I strangely reveled in the freedom I had to enjoy my surroundings and form new friendships with graduate school students from the lab. We explored The Inner Harbor at night, attended a concert together one weekend, and even got to watch the Orioles lose (to nobody's surprise). Ironically, it's through these new friendships I discovered something unexpected: what I truly love is sharing research. Whether in a presentation or in a casual conversation, making others interested in science is perhaps more exciting to me than the research itself. This solidified a new pursuit to angle my love for writing towards illuminating science in ways people can understand, adding value to a society that can certainly benefit from more scientific literacy.


It seems fitting that my goals are still transforming: in Scarry's book, there is not just one goldbug, there is one on every page. With each new experience, I'm learning that it isn't the goldbug itself, but rather the act of searching for the goldbugs that will encourage, shape, and refine my ever-evolving passions. Regardless of the goldbug I seek -- I know my pickle truck has just begun its journey.


文章来自于塔夫茨大学官网:

https://admissions.tufts.edu/apply/advice/past-essays/common-application-essays/



生词:


1. nanoparticles [nænəu'pa:tiklz] n. 纳米粒子(nanoparticle的复数形式) 

2. macrophages [ˈmækroʊˌfeɪdʒɪz] 巨噬细胞; 巨噬細胞; 巨嗜细胞; 噬细胞; 吞噬细胞;

3. nanomedicine 纳米医学; 纳米医药;

4. chemotherapeutic [ˌkemoʊˌθerə'pjutɪk] adj. 化疗的;化学治疗的;

5. fluorescent dye [ˌflɔːˈresnt daɪ] 荧光染料;

6. cyclophosphamide 环磷酰胺,癌得星,安道生(免疫抑制剂及抗肿瘤药)



解析:

 


1. My first dream job was to be a pickle truck driver.


Pickle是美国人餐桌上必不可少的佐料小菜,我们主人公以这样的一个微乎其微的平凡梦想开篇,不禁让人心里产生疑问:这样一个渺小的愿望,甚至都算不上梦想啊,这已经平凡到几乎人人都可以实现啊!这样的愿望会对作者产生什么样的影响呢?一连串的问号之后,吸引着读者们跟着主人公的“酸黄瓜”货车一路向前。


2. I would imagine the wonderful life I would have: being a pig driving a giant pickle truck across the country, chasing and finding goldbug. I then moved on to wanting to be a Lego Master. Then an architect. Then a surgeon.


作者受到儿时故事书里面情节的影响,坚信着只要自己开着酸黄瓜货车不停工作,就最终一定能获得goldbug,有了goldbug就会有幸福和快乐的生活,作为一个小孩子,这是一个多么朴实的愿望。这其实是一个伏笔,预示着作者更大的梦想。


3. Then I discovered a real goldbug: gold nanoparticles that can reprogram macrophages to assist in killing tumors, produce clear images of them without sacrificing the subject, and heat them to obliteration.


随着作者学术经历的不断积累,他的酸黄瓜卡车承载着他最初的梦想,找到了人生中真正的goldbug。这是本篇的一个转折,直接切入正题,把读者的注意力引入到了科研领域。这里有引发了读者的疑问:他找到goldbug了么?


4. Even with moving frequently between hotels, AirBnB's, and students' apartments, I strangely reveled in the freedom I had to enjoy my surroundings and form new friendships with graduate school students from the lab.


这里和文章开篇形成了一番小的呼应:从儿时的故事中,幻想着开着自己的“酸黄瓜”货车,经过各种地方,去寻找goldbug。而在自己长大后,随着自己身处环境的变化,接触不同人群的变化,与不同人群交流内容的变化,不断刷新了自己对人生真正的goldbug的认识。


5. Ironically, it's through these new friendships I discovered something unexpected: what I truly love is sharing research. Whether in a presentation or in a casual conversation, making others interested in science is perhaps more exciting to me than the research itself.


作为该段落的ending sentence,很好的诠释了作者自己找寻到的自己的梦想。作为一名科学研究者,他更希望通过自己的方式能够让更多的人知晓,科学研究其实距离大家并不遥远,同时也寓意着我们的作者希望通过自己的方式,让大家能够正视疾病带给大家的影响。


6. With each new experience, I'm learning that it isn't the goldbug itself, but rather the act of searching for the goldbugs that will encourage, shape, and refine my ever-evolving passions. Regardless of the goldbug I seek -- I know my pickle truck has just begun its journey.


随着作者在科学探索之路上的不断尝试,他发现了自己的梦想已经脱离开了儿时故事书中的goldbug, 自己的目标不是要找到goldbug,而是自己在寻找goldbug的过程所经历的的一切带个自己的感受,这个感受一定是甜酸苦辣咸,五味杂陈的。这也同时寓意着在科学探索之路上,定会遇到各种困难,但是作者会坚定的开着自己的“酸黄瓜”货车(代表着自始至终坚守着儿时的愿望),为了找到自己科研之路上的goldbug,一路向前。

 

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